The Americans struck on six of their 12 shots, and the first four shots of the game were all goals -- three for the USA and one for Canada in the first 28 minutes.
Wearing special pink uniforms in support of breast cancer awareness, the U.S. women got two goals from Abby Wambach and goals from Kristine Lilly, Lindsay Tarpley, Lori Chalupny and Heather O'Reilly.
"They threw a lot of numbers forward and that's why you saw a lot of goals in this game," said Ryan. "They threw numbers forward, and then we countered and had great chances. Our set plays were very good tonight as well. We scored off two long balls and a great cross from Kristine Lilly, as well as a long throw that Abby flicked on to Carli [Lloyd], who laid it in to Lil. Set pieces are always a big thing and we produced tonight."
MITTS INJURY. Heather Mitts went down about 25 minutes into the game and had to be replaced by Stephanie Lopez. Mitts injured her left knee in a clash at midfield and will have an MRI to determine the extent of the injury.
U.S. defender Kate Markgraf started and played the first 53 minutes after coming back from injuries that caused her to miss the last five matches. Defender Marian Dalmy came on for Markgraf to earn just her second cap with the senior national team.
May 12 in Frisco, Texas
USA 6 Canada 2. Goals: Wambach pen. 3, 65, Tarpley 13, Chalupny 28, Lilly 35, O'Reilly 73; Wilkinson 11, Sinclair 50.
USA -- Solo, Mitts (Lopez, 27), Whitehill, Markgraf (Dalmy, 53), Rampone, Boxx, Chalupny (Wagner, 72), Lloyd (Osborne, 58), Tarpley (O'Reilly, 62), Wambach (Kai, 82), Lilly.
Canada -- McLeod, Thorlakson (Kiss, 72), Hermus, Franko, Timko, Matheson (Schmidt, 79), Neil (Lang, 46), Walsh, Chapman, Sinclair, Wilkinson (Robinson, 85).
Referee: Sandra Serafini (USA).