Guadalajara and Club America, Mexico's two most popular clubs, will meet in one semifinal, while regular-season leader Pachuca, which edged Santos on the tiebreaker (better regular-season record), meets Cruz Azul in the other semifinal.
Cuauhtemoc Blanco, the Chicago Fire's signee, was the star of the second leg of the quarterfinals, firing two goals for Club America in its 4-1 win over Atlas.
America faces another hectic week on two fronts. It's scheduled to face Santos of Brazil in the first leg of their Libertadores Cup quarterfinals series on Wednesday at Azteca Stadium. The Mexican federation will set the dates and times of the two Clausura semifinal series on Monday morning.
Quarterfinals, Second Leg
Cruz Azul 1 (Nunez 47) UAG 0.
(Cruz Azul wins 2-0 on aggregate.)
Guadalajara 3 (Own goal 43, 76, Bautista pen. 77) Tigres 2 (Lozano pen. 28, Fonseca 83).
(Guadalajara wins 6-2 on aggregate.)
Club America 4 (Blanco 13, pen. 77, Fernandez 39, Mosquera 82) Atlas 1 (Navia 48).
(Club America wins 7-4 on aggregate.)
Pachuca 1 (Salazar 64) Santos 1 (Jimenez 68).
(Aggregate: 2-2; Pachuca advances on its better regular-season record.)