The novelty of the World Cup 2010 qualifying draw in Africa is that World Cup 2010 host South Africa will take part in qualifying since the competition also serves as qualifying for the 2010 African Nations Cup. The Bafana Bafana were drawn with powerhouse Nigeria, Equatorial Guinea and Sierra Leone in the first group stage.

FIRST GROUP STAGE: Following a preliminary round, the 48 teams remaining teams were drawn in 12 groups of four. The 12 group winners and eight best runners-up advance to final stage;

FINAL GROUP STAGE: The 20 teams will be drawn in five groups of four. The five group winners qualify for the finals.

(Note: World Cup 2010 host South Africa takes part in the competition which also serves as the qualifying tournament for the Africa Nations Cup. If South Africa reaches the final stage, its matches will not count toward World Cup qualification.)

DRAW:

Group 1
Cameroon
Cape Verde Islands
Tanzania
Mauritius

Group 2
Guinea
Zimbabwe
Namibia
Kenya

Group 3
Angola
Benin
Uganda
Niger

Group 4
Nigeria
South Africa
Equatorial Guinea
Sierra Leone

Group 5
Ghana
Libya
Gabon
Lesotho

Group 6
Senegal
Algeria
Liberia
Gambia

Group 7
Ivory Coast
Mozambique
Botswana
Madagascar

Group 8
Morocco
Ethiopia
Rwanda
Mauritania

Group 9
Tunisia
Burkina Faso
Burundi
Seychelles

Group 10
Mali
Congo
Sudan
Chad

Group 11
Togo
Zambia
Eritrea
Swaziland

Group 12
Egypt
DR Congo
Malawi
Djibouti