Scottish champion Celtic travels to defending champion AC Milan needing a point to clinch the second berth in the group. Milan has already wrapped up one berth.
If Celtic loses, Shakhtar Donetsk will claim the second berth if it beats Benfica.
The best the Lisbon club can do is claim third place ahead of Shakhtar with a win in Ukraine on Tuesday and take the UEFA Cup berth for the third-place team.
ESPN2 AC MILAN-CELTIC (live), 2:40 pm.
ESPN DEPORTES AC MILAN-CELTIC (live), 2:40 pm.
ESPN DEPORTES SHAKHTAR DONETSK-BENFICA (delay), 4:45 pm.