Paloschi scored with his first touch in a Serie A game when he struck a superb goal to give Milan a 1-0 win over Siena.
Paloschi needed all of 16 seconds to score his first league goal. He came on in the 63rd minute and raced forward to connect with a volley after the ball was played ahead to him at the edge of the penalty area.
Milan has been hit hard by injuries -- World Player of the Year Kaka and Alexandre Pato are both out -- so it called up Paloschi, who had played last week for its primavera team playing in the Viareggio Tournament.
Paloschi had scored twice in two games for Milan in the Coppa Italia.