Ayers suffered facial fractures that could sideline him for a lengthy period. Cochrane will be evaluated periodically over the next few days to gauge the severity of his concussion.
"It shocked us a little bit," said Coach Frank Yallop, who brought on Jason Hernandez and James Riley as emergency replacements. "It was a pretty bad collision to be honest. I was sitting pretty close to it, and it was loud and I think it disturbed a few of our guys."
San Jose, playing a mostly reserve lineup, lost 4-0 to Real Salt Lake at Rice-Eccles Stadium in conditions harsh enough that snowfall in the second half required use of an orange ball.
The team announced Wednesday that less than 800 tickets remain for the Buck Shaw opener Saturday against FC Dallas.
Director of broadcasting and communications Jed Mettee sent an e-mail to correct an error in a previous story regarding the facility's capacity.
Official capacity will be 10,300, which can be increased to 10,500 by use of standing-room tickets, making Buck Shaw slightly larger than CommunityAmerica Ballpark, a minor-league baseball stadium being used by the Kansas City Wizards while renovations are conducted at Arrowhead Stadium.