LP Field, which has a capacity of 68,798, is home of the NFL's Tennessee Titans and Tennessee State University football.
The men's U.S. full national team has played once before in Nashville, a 2006 World Cup preparation game against Morocco that drew 26,141.
Last April, the venue hosted the knockout round of the Concacaf Olympic Qualifying tournament, where the U.S. U-23 men defeated Canada in the semifinals to become one of two teams from the region to qualify for Beijing.
USA FIFA World Cup Qualifying Schedule
Feb. 11 vs. Mexico Columbus, Ohio
March 28 at El Salvador
April 1 vs. Trinidad & Tobago Nashville, Tenn.
June 3 at Costa Rica
June 6 vs. Honduras
Aug. 12 at Mexico
Sept. 5 vs. El Salvador
Sept. 9 at Trinidad & Tobago
Oct. 10 at Honduras
Oct. 14 vs. Costa Rica