Both Inter Milan and Lyon failed in their bids to clinch their respective league titles on Wednesday.

Inter Milan lost for the first time this season when it fell, 3-1, to second-place Roma at home. Inter's hopes of sealing its second successive Scudetto were dashed as late second-half goals from Francesco Totti and Marco Cassetti sealed Roma's win

Lyon all but mathematically wrapped up a record sixth French title in a row when it was held to a 0-0 tie by Rennes at home.

Lyon is 18 points ahead of second-place Toulouse with six games to play. Lyon has to lose all six games and Toulouse would have to win all of its games by a combined margin of 27 goals for Toulouse to overtake Lyon.

In England, Chelsea cut Manchester United's lead in the Premier League to three points when the Blues won, 4-1, at West Ham on Wednesday.

England winger Shaun Wright-Phillips scored two spectacular goals from in a five-minute span during the first half to lead Chelsea. Goals after the break from Ivorians Salomon Kalou and Didier Drogba sealed the victory.

Liverpool regained third place with a 2-0 win over Middlesbrough thanks to two goals from Steve Gerrard. Arsenal is fourth, eight points ahead of Everton and Bolton with four games to play.