T&T blew a 2-0 lead and had to settle for a 2-2 tie at El Salvador last month, and the Catrachos lost to Costa Rica, 2-0, so both teams cannot afford a loss on Day 2 of the Hexagonal.
The Soca Warriors are without captain Dwight Yorke, goalie Clayton Ince and midfielder Chris Birchall -- all suspended -- for Saturday's game.
Jan Michael Williams of Hungarian club Ferencvaros should replace Ince in goal, while Jason Scotland (Swansea City), Stern John (Bristol City), Kenwyne Jones (Sunderland) return from their English league clubs to lead the T&T attack.
Honduras will be missing star David Suazo, who is injured. Edgar Alvarez, Walter Martinez and Saul Martinez will also be absent.
The Catrachos' squad includes MLS players Amado Guevara (Toronto, USA) and Roger Espinoza (Kansas City) and former MLS players Samuel Caballero, Ramon Nunez and Carlos Pavon.