Tim Howard was the only American to earn a win in Monday's slate of English Premier League games when Everton beat Burnley, 2-0 for its first victory at home in nine games.
Everton won with two goals in the last seven minutes to climb to 11th place in the EPL.
Clint Dempsey, Marcus Hahnemann and Jonathan Spector played in losing efforts.
Dempsey's Fulham led West London rival Chelsea after four minutes, but the Blues rallied for a 2-1 win thanks to a Didier Drogba header and Chris Smalling own goal.
Hahnemann's Wolves lost, 3-0, at home to Manchester City, which won its second straight game under new manager Roberto Mancini.
Jonathan Spector came on as a sub for West Ham in the 19th minute of its game at Tottenham. The Hammers' 2-0 loss left them on the edge of the relegation zone with more games played than the three teams below them.
In the League Championship, Jay DeMerit played the entire game for Watford in its 2-2 tie at Bristol City.