Houston fell to Charleston on penalty kicks, 4-3, after a 1-1 tie in regulation and overtime, during which the Battery played the last 17 minutes with nine men.
Crystal Palace Baltimore beat New York, 2-0, playing 10-v-11 from the 34th minute.
There weren't any red cards in the Seattle-Chivas USA showdown, but that didn't help the MLS squad. Seattle prevailed, 2-0. Ex-Wizard Taylor Graham, assisted by former Galaxy midfielder Josh Gardner, scored two minutes before halftime, and Sebastien Le Toux added a late clincher for the Sounders.
The other five MLS teams managed to avoid being upset, though two survived harrowing escapes.
FC Dallas needed a last-minute strike from Abe Thompson -- his second goal of the game -- to knock off Miami (USL-1), 2-1, and Kansas City rallied from two goals down to knock off Carolina (USL-1), 4-2, in overtime.
Defending cup winner New England beat Richmond (USL-2), 3-0; Chicago pounded Cleveland (USL-2), 4-1; and D.C. United downed Rochester (USL-1), 2-0.
In the case of Houston, Coach Dominic Kinnear can't be faulted for fielding mostly reserves; the defending champion drew the Thursday night ESPN2 slot this week, and will be on the unforgiving carpet of Rice-Eccles Stadium to take on Real Salt Lake. Ex-Toronto FC player Marco Reda opened the scoring for Charleston, and Steve Wondolowski's late equalizer with Houston playing up a man forced overtime.
The Battery played the final 20 minutes of regulation a man down after midfielder Chris Corcoran was sent off, and Reda followed him with two minutes left in the first overtime, but Charleston held out and prevailed on penalties.
The Red Bulls lost to a USL Second Division team despite starting with regulars Kevin Goldthwaite, Carlos Mendes, Mike Magee, Jeff Parke and Luke Sassano on the field, and longtime veteran Zach Thornton in goal. Andrew Marshall scored in the 18th minute, and former Rev Ibrahim Kante went off in the 34th minute with a second yellow. Sinisa Ubiparipovic, John Wolyniec and Andrew Boyens came on at halftime with the Red Bulls trailing, 1-0, but Gary Brooks scored with 15 minutes left to finish off New York.
Revs coach Steve Nicol used the match to speed along the rehabilitation of forward Taylor Twellman, and he scored New England's third goal six minutes before being subbed in the 73rd minute.
Midfielder Chris Tierney set up Twellman's goal as well as an opening strike from Sam Brill, with Joe Germanese getting the other goal. Both Brill and Germanese registered their first goals for the Revs, and first-round 2008 draft choice Rob Valentino, who still coming back from knee surgery, played the full 90 minutes.
Midfielder Ben Olsen didn't dress for United in a match that featured Marc Burch, Devon McTavish and keeper Zach Wells as the only regulars to play all 90 minutes. Burch scored both goals as D.C. needed 75 minutes to break through. Gonzalo Martinez, Fred, Luciano Emilio and Clyde Simms each played 45 minutes.
Fire coach Denis Hamlett started three of his attacking regulars - Chris Rolfe, Chad Barrett and Calen Carr - yet reserve forward Mike Banner scored twice in Chicago's victory. Carr set up one of Banner's goals and scored another himself, and Rolfe earned a penalty kick that Barrett converted.
Hamlett also used the match to introduce Lider Marmol, who made his first appearance after suffering a knee injury following a drawn-out struggle with New York for his playing rights.
Colombian striker Ivan Trujillo has scored just one goal in 10 league games for Kansas City, but after scoring to start the Wizards' comeback against Carolina he also netted the eventual winning goal three minutes into overtime. Ryan Pore and Claudio Lopez converted penalty kicks to frustrate the Railhawks, who led 2-0 midway through the second half on goals by Santiago Fusilier and Matthew Watson before succumbing.
Ryan Solle, another former Rev, was sent off with 12 minutes left, but Kansas City - leading, 3-2 - refused to be flustered with the man advantage, and Pore converted his penalty in the final minutes to lock down the victory.
Crystal Palace Baltimore 2 New York Red Bulls 0
CPB: Andrew Marshall (Bryan Harkin) 17
CPB: Gary Brooks (Paul Robson) 75
New England Revolution 3 Richmond Kickers 0
NE: Sam Brill (Chris Tierney) 46
NE: Joe Germanese (Chase Hilgenbrinck) 63
NE: Taylor Twellman (Chris Tierney) 67
Charleston Battery 1 Houston Dynamo 1
(Charleston wins 4-3 on penalties.)
CHA: Marco Reda (Ian Fuller) 31
HOU: Stephen Wondolowski 89
Carolina Railhawks 2 Kansas Citu Wizards 4
CAR: Santiago Fusulier (Ryan Solle) 43
CAR: Matthew Watson (Dan Antoniuk) 57
KC: Ivan Trujillo (Michael Harrington) 67
KC: Claudio Lopez (pen.) 81
KC: Ivan Trujillo 93
KC: Ryan Pore (pen.) 119
D.C. United 2 Rochester Rhinos 0
DC: Marc Burch (unassisted) 78
DC: Marc Burch (unassisted) 85
Chicago Fire 4 Cleveland City Stars 1
CHI: Mike Banner (unassisted) 13
CHI: Calen Carr (Stephen King) 23
CHI: Chad Barrett (PK) 26
CLE: Kiel McClung (Adam Ruud) 61
CHI: Mike Banner (Peter Lowry) 73
FC Dallas 2 Miami FC Blues 1
MIA: Alex Afonso (unassisted) 7
FCD: Abe Thompson (Dominic Oduro) 48+
FCD: Abe Thompson (Drew Moor) 92+
Seattle Sounders 2 Chivas USA 0
SEA: Taylor Graham (Josh Gardner) 43
SEA: Sebastien Le Toux (unassisted) 83