The 18 MLS playoff teams released 28 players on international duty during the November window.
Update: Costa Rica called uo Crew winger Luis Diaz.
That includes players headed to play in World Cup 2022 qualifying in South America, the Euro 2020 playoffs and UEFA Nations League qualifying in Europe, Africa Cup of Nations 2021 qualifying and friendlies involving four Concacaf teams.
Because of MLS quarantine requirements for players arriving or returning from abroad, players on international duty will miss the MLS play-in round and round one of the conference playoffs.
At least one player is expected to be exempt from quarantining: Seattle's Raul Ruidiaz, who was designated as a "recovered person" last month after testing positive for COVID-19 in October while on international duty with Peru.
The Seattle-LAFC game, a rematch of the 2019 Western Conference final the Sounders won en route to their second MLS Cup title, is the match most affected. Seven players on the two teams -- including Ruidiaz -- have been called up. LAFC has four players in South America for World Cup 2022 qualifying.
Eastern Conference, Play-In Round:
Nov. 20. No. 7 Nashville SC vs. No. 10 Inter Miami
Nashville SC (1): Randal Leal (Costa Rica)
Inter Miami (2): Rodolfo Pizarro (Mexico), Alvas Powell (Jamaica)
Nov. 20. No. 8 New England vs. No. 9 Montreal
New England (0)
Montreal (2): Jukka Raitala (Finland), Victor Wanyama (Kenya)
Eastern Conference, Round One:
Nov. 21. No. 3 Columbus vs. No. 6 NY Red Bulls
Columbus (1). Luis Diaz (Costa Rica).
NY Red Bulls (2): Cristian Casseres Jr. (Venezuela), Kaku (Paraguay)
Nov. 21. No. 4 Orlando City vs. No. 5 NYCFC
Orlando City (2): Pedro Gallese (Peru), Sebastian Mendez (Ecuador)
NYCFC (1): Alexander Callens (Peru)
Nov. 24. No. 1 Philadelphia vs. lower advancing play-in seed
Philadelphia (2): Olivier Mbaizo (Cameroon), Jamiro Monteiro (Cape Verde).
Nov. 24. No. 2 Toronto FC vs. higher advancing play-in seed
Toronto FC (0).
Western Conference, Round One
Nov. 22. No. 1 Sporting KC vs. No. 8 San Jose
Sporting KC (0).
San Jose (1): Marcos Lopez (Peru)
Nov. 22. No. 3 Portland vs. No. 6 FC Dallas
Portland (2): Andy Polo (Peru), Felipe Mora (Chile)
FC Dallas (0).
Nov. 22. No. 4 Minnesota United vs. No. 5 Colorado
Minnesota United (4): Robin Lod (Finland), Jan Gregus (Slovakia), Kei Kamara (Sierra Leone), Romain Metanire (Madagascar)
Colorado (1): Diego Rubio (Chile)
Nov. 24. No. 2 Seattle vs. No. 7 LAFC
Seattle (3): Xavier Arreaga (Ecuador), *Raul Ruidiaz (Peru), Gustav Svensson (Sweden).
LAFC (4): Brian Rodriguez (Uruguay), Diego Rossi (Uruguay), Jose Cifuentes (Ecuador), Diego Palacios (Ecuador).
*Designated recovered person.