Manchester City hosts Sunderland on Sunday.

The USA hosts Argentina in a friendly on Saturday, which is also full of European Championship qualifiers and MLS Week 2 action.

Midweek action includes Copa Libertadores games. European Championship qualifiers start on Friday. The USA hosts Argentina in a friendly on Saturday.

Los Angeles hosts New England in Sunday MLS action. In England, Manchester City clashes with Chelsea.

There's a full slate of MLS games on the first weekend of the 2011 season. Fox Soccer, which will be airing 31 regular-season games -- 14 on Friday nights and 17 Saturday nights -- starts with coverage of defending champion Colorado hosting newcomer Portland on Saturday. Spanish-language Telefutura airs Los Angeles-New England on Sunday. MLS games not broadcast by national outlets are available on the Direct Kick package, which costs $79 for the year more than 200 games and is free this weekend.

On Saturday, Manchester United and Arsenal clash in the FA Cup quarterfinals. Spanish La Liga leader Barcelona plays on Sunday.

There's Italian Serie A action on Friday. On Saturday, Manchester United and Arsenal clash in the FA Cup quarterfinals.

Among the weekend's intriguing matchups: Liverpool hosts Manchester United on Sunday.