Republic FC players and fans celebrate the 2022 Open Cup semifinal win. (Photo: Sacramento Republic FC)

MLS teams dominated lower-division opposition in the 2025 U.S. Open Cup, going 15-1 in the round of 32, but seven USL teams entered in the 2026 round of 32 have pulled off “cupsets,” including three teams with four or more wins against MLS foes.

Cupset winners
Sac Republic FC (6)
2017 
Real Salt Lake 4-1 2018 Seattle Sounders 2-1 2022 San Jose Earthquakes 2-0, LA Galaxy 2-1, Sporting KC 0-0 (5-4) 2024 San Jose Earthquakes 2-0
Richmond Kickers (5)

2000 Colorado Rapids 3-0 2004 D.C. United 2-1 2007 LA Galaxy 1-0 2011 Sporting KC 2-0, 2011 Columbus Crew 2-1.
Pittsburgh Riverhounds (4)
2001 Colorado Rapids 2-0 2023 New England Revolution 1-0, Columbus Crew 1-0 2025 NYCFC 1-0.
Union Omaha (2)
2022: Chicago Fire 2-2 (5-4), Minnesota United 2-1
Charlotte Independence (1)
2015 New England Revolution 1-0.
Louisville City (1)
2018: New England Revolution 3-2
Detroit City FC (1)
2024 Houston Dynamo 3-3 (10-9)

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Paul Kennedy is the Editor in Chief & General Manager of Soccer America.